Systemic sclerosis

All of the following are features of Scleroderma

except

Patients with Systemic Sclerosis have elevated serum titers for which of the following pathogens? 

A 40-year-old female patient was referred to Oral and Maxillofacial Radiology Department, Istanbul University Faculty of Dentistry for dental complaints. Her medical history and the documentation she presented she had goiter and gastric disease. Extra-oral examination showed that the patient was not able to open her hands because of sclerosis and had a narrow nose because of atrophy of alanasi. Decreased number of wrinkles were also observed. Upper lip was insufficient to cover maxillary teeth, which is also known as “mouse-like face”. Anamnesis revealed that the patient had Raynaud phenomenon. She had used cortizon and acetylsalicylic acid for twenty years due to the vascular decomposition. Although Raynaud’s phenomenon and acrosclerosis were present in our case, there was no internal organ involvement. Patient complained about the dryness of her mouth and multiple caries lesions were observed.

1. Formulate a preliminary diagnosis.

Indication of poor prognosis of systemic sclerosis is: